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Washington University Experience | PERIPHERAL NEUROPATHY | 9B PERINEURITIS & PERINEURIAL PATHOLOGY | 11A0 Case 11 History
Case 11 History ---- The patient is a 42-year-old man, with a long history of recreational drug use, who presented with acute onset weakness and numbness in the right foot, and a few weeks later, in the left. Clinical concern was immune-mediated neuropathy. Nerve conduction study showed an asymmetric, primarily axonal neuropathy. Electromyography showed evidence for denervation of peroneal-innervated muscles on the left, and of peroneal- and tibial-innervated muscles on the right. Operative procedure: Right gastrocnemius muscle biopsy and right sural nerve biopsy. ---- Not shown: Smooth muscle actin (SMA) immunoreactivity shows ostensibly normal appearing smooth muscle cells distributed within vessel walls and other cells in the perineurium.
