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Washington University Experience | PERIPHERAL NEUROPATHY | 9B PERINEURITIS & PERINEURIAL PATHOLOGY | 12B6 Perineurium, organelles (Case 12) EM 046 - Copy

derived from delicate cells which rupture? (electron micrographs) ---- Not shown: The ultrastructural picture is that of removal of normal myelin from an intact axon suspicious for macrophage-mediated demyelination as can be seen in CIDP. There are no well-formed onion bulbs and few endoneurial inflammatory cells. The ultrastructural appearance of this biopsy is consistent with, but not pathognomonic of, the patient's history of CIDP.

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