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Washington University Experience | PRION DISEASES | Prion Diseases | 11B1 CJD, (Case 11) H&E cerebellum 20X.jpg
The molecular layer in the cerebellum is mildly involved. (H&E) ---- The diagnosis of sporadic CJD MM1is supported by the NPDPSC findings of immunoblot demonstration of abnormal protease resistant prion protein (PrP27-30), 3F4 immunohistochemistry, and PrP gene sequencing (the patient does not have a familial form).