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Washington University Experience | PRION DISEASES | Prion Diseases | 12A1 Variant CJD AANP 1997-04
Case 12 ---- This is a 29 year old woman with a 17 month history of a progressive dementing illness associated with ataxia and choreiform movements. She deteriorated despite supportive therapy and died in January 1996. Permission for autopsy was restricted to the brain and internal organs. ---- At autopsy the patient was an emaciated young woman with muscle wasting and fixed flexion deformities of the limbs. The brain weighed 1122g and showed global atrophy. No focal abnormality was noted on section of the fixed brain. Material submitted: H&E section of cerebrum. ---- Shown is a whole mount of the cerebral cortex which appears deceptively minimally involved at this magnification. (H&E)
