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Washington University Experience | PRION DISEASES | Prion Diseases | 12A8 CJD, new variant (AANP 1997-04) H&E 60X 2
Multiple plaques may coalesce into large aggregates. (H&E) ---- Comment: The pathology is quite uniform throughout the cerebral cortex, and hence a cerebral biopsy is likely to disclose the characteristic plaques with spongiform change. In addition, PrP can be demonstrated in biopsy of the tonsil.
