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Washington University Experience | PRION DISEASES | Prion Diseases | 15B2 CJD (Case 15) 3 extended survival H&E N1 10X (scale bar)
15B2,3 Sections show a triad of histopathologic changes: neuronal cell depopulation. spongiform change and dense astrocytic gliosis. The spongiform change consisting of small neuropil vacuoles is most prominent in the cerebral cortex and deeper subcortical gray matter.
