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Washington University Experience | PRION DISEASES | Prion Diseases | 22A1 CJD (Case 22) 3
At autopsy the brain was not weighed for fear of contamination. ---- 22A1,2 There was marked cortical atrophy described in the frontal and occipital poles most readily, but gyral narrowing to a lesser degree is present diffusely. Furthermore, the cortical ribbon shows significant narrowing diffusely, averaging 2-3 mm in width. The centrum semiovale and convolutional white matter appear correspondingly diminished in size.