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Washington University Experience | PRION DISEASES | Prion Diseases | 22C1 CJD (Case 22) H&E O WM
22C1,2 Purkinje and granular cell loss were prominent in all sections. Spongiform changes extended through all cortical layers into the underlying white matter. Bergmann gliosis and fibrillary gliosis in the granular layer was present. Loss of white matter fibers was prominent.
