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Washington University Experience | PRION DISEASES | Prion Diseases | 2D2 CJD (Case 2) H&E 7
2D2-4 Higher magnification images of the neocortex in multiple lobes shows marked neuronal loss, and extensive astrocytosis with a limited degree of residual spongiform vacuolation. The neuron loss and astrocytosis clearly is transcortical. Adjacent superficial white matter is gliotic.
