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Washington University Experience | PRION DISEASES | Prion Diseases | 9A2 CJD (Case 9) N4 H&E 20X 1
H&E stained sections show global involvement of the brain by spongiform changes. The frontal and temporal cortices show severe spongiform neurodegenerative changes including microvacuolation of the cortex, neuronal loss, and gliosis.