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Washington University Experience | VASCULAR | Amyloid-Beta Related Angiitis (ABRA) | 9A0 Case 9 History
Case 9 ---- The patient is a 69-year-old woman with a history of type II diabetes, COPD, and coronary artery disease who presented with a week history of headaches, hallucinations and altered mental status. MRI at admission showed numerous scattered FLAIR hyperintense lesions in the cerebral white matter throughout the centrum semiovale and juxtacortical regions as well as more confluent FLAIR hyperintensity along the periventricular region. The differential diagnosis was thought to include vasculitis, lymphoma (in particular intravascular lymphoma), atypical demyelination, and less likely neurodegenerative disease such as cerebral amyloid angiopathy, and progressive chronic microvascular ischemic changes. Operative procedure: Right brain (parietal) stealth-guided open biopsy. Her mental status improved with IV steroids.
