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Washington University Experience | VASCULAR | Congophilic Angiopathy (CAA) | 6A0 Case 6 History
Case 6 History ---- The patient was a 70-year old man with a family history significant for a mother with AD. He presented initially with memory and cognition problems 8 years ago. Four years ago, the cognitive and memory changes were severe enough to be noted by friends and were progressive. Following hernia surgery he had active visual hallucinations and behavioral changes. MRI demonstrated cerebral atrophy and diffuse slowing on EEG. Given his slow progressive decline, he was diagnosed with dementia of Alzheimer type. In Feb 2009, he was assigned a clinical dementia rating score of 1. By 2010, further deterioration required complete care. He also developed parkinsonian symptoms. In October 2011 he was placed in hospice care. At the time of his last visit to BJH in November 2011 he was mute, uncooperative for exam, and had developed bilateral pneumonia. Medications at this time included Aricept, Namenda, Sinemet, and Depakote. The patient was discharged to hospice care and died 9 days later. ---- Autopsy findings included Alzheimer disease, dementia with Lewy bodies and idiopathic Parkinson disease, arteriolosclerosis, cerebral amyloid angiopathy with patchy amyloid beta related angiitis (ABRA)
