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Washington University Experience | VASCULAR | Hypoxia-Ischemia, adult | Hippocampus | 1C4 Hypoxia-Ischemia (Case 1) H&E N13 2 copy
Neurons of the dentate gyrus tend to be largely spared except in severe hypoxia/ischemia. In this case there are numerous residual dentate neurons infiltrated by small astrocytes. In comparison, the adjacent CA4 region (arrow) is completely depopulated and gliotic. (H&E)