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Washington University Experience | VASCULAR | Respirator Brain (In Vivo Autolysis) | 4B7 Autolysis (Respirator Brain) (Case 4) N9 H&E
4B7 Purkinje cells stand out against the pale parenchyma but do not show marked eosinophilia or the pyknotic nuclear changes of typical cerebellar hypoxia/ischemia, a change that takes some time to develop in vivo. In this case it appears that metabolic ketoacidosis resulted in edema, failure to perfuse the intracranial contents and in vivo autolysis (H&E)
