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Washington University Experience | VASCULAR | Vasculitis - Giant Cell Arteritis | 4E1 Vasculitis, temporal artery, (Case 4) MAC 38 2 (2)
4E1,2 There is strong staining for the membrane attack complex, proteins which typically form as a result of the activation of the complement system, which results in the formation of pores that disrupt the cell membrane of target cells, leading to cell lysis and death. (MAC IHC)